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Close relatives of people with blood cancer are more likely to be diagnosed with the disease themselves, a major study has found. An international team, led out of the Institute of Cancer Research in London, examined diagnosis, birth and death records of more than 150,000 people with all types of blood cancer — such as leukaemia, lymphoma or myeloma...
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According to findings from a study published in Cancer on the utilization of specific supportive care measures in older patients with multiple myeloma, only approximately two-thirds of patients received guideline-concordant administration of a bone-modifying agent. The course of treatment for patients with multiple myeloma is typically characterized by the administration of multiple lines of therapy associated with periods...
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A Phase II study of a GlaxoSmithKline drug to treat the blood cancer multiple myeloma has been successful, the company said Friday. The London-based drugmaker said it had positive headline results from the DREAMM-2 study of GSK2857916 (belantamab mafodotin), an antibody-drug conjugate that targets the antigen BCMA. It did not provide details of the data, but said...
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A combination of humanized anti-CD19 and anti-B-cell maturation antigen chimeric antigen receptor T-cells has shown activity in patients with relapsed or refractory multiple myeloma, according to results of a single-center, single-arm phase 2 clinical trial published in The Lancet Haematology. The dual CAR T-cell combination resulted in a 95% response rate, with 43% of patients achieving...
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This story was originally published on Stuff “Why does New Zealand need to reinvent the wheel?” Posed by National MP Maggie Barry, that was the question at the heart of a fight to have dozens of life-extending – and life-saving – drugs funded. Emotions ran high during Wednesday’s health select committee as plea after plea...
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This story was originally published on RNZ Politicians heard emotional pleas today from cancer survivors, people with disabilities and health agencies to boost Pharmac’s funding for life saving drugs. Petitions were presented to the Health Select Committee at Parliament – calling on medicines to be funded – including for breast, lung, ovarian cancers, along with...
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Dr Ken Romeril, chief executive, Myeloma New Zealand, is appearing today before the Health Select Committee in support of their submission asking for funding of six life-extending treatments for multiple myeloma patients. Dr Romeril said there have been huge advances in myeloma treatment internationally, but no new anti-myeloma medicines have been funded in NZ in...
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Omar Nadeem, MD, a physician at Dana-Farber Cancer Institute and an instructor in medicine at Harvard Medical School, discusses individualizing therapy for patients with multiple myeloma. As more therapies become available, more thought will have to be put into determining how best to sequence agents. In the relapsed setting, that will be the most important...
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This story was originally published on the Hematology Advisor The introduction of monoclonal antibodies and immunomodulators into earlier lines of therapy may improve progression-free survival (PFS) in patients with refractory multiple myeloma (MM), according to a study reanalyzing clinical data collected at the Winship Cancer Center at Emory University in Atlanta, Georgia. Results were published in Cancer....
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A new drug reduced the risk of relapse and increased survival by five months, according to a recent study. The results were presented at a cancer conference in Chicago in June. Most often found in bone marrow sites, multiple myeloma is considered a chronic disease, although several new treatment options have increased the survival rate...
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