Article of the Week: Delineation of the timing of second-line therapy post–autologous stem cell transplant in patients with AL amyloidosis

For this week’s Article of the Week, we look at an article that describes a review of patient data from the Mayo Clinic.  The study sought to identify factors that could guide re-treatment in AL amyloidosis, with the goal of preventing organ progression.  Covering a period 1996-2014, the timeframe necessarily included a range of treatment approaches.  Nevertheless, in this cohort, relapse/progression status prior to institution of second-line therapy could predict outcomes.  Additionally, organ progression could occur in the absence of evidence of haematologic progression.

Read the full article here.