While chimeric antigen receptor (CAR)-T cell therapy has demonstrated positive response rates in children with relapsed and/or refractory CD19-positive acute lymphoblastic leukemia (ALL), severe toxicities can also be associated with such treatment. So, a group of researchers issued guidelines to help ensure these patients experience optimal outcomes. “These guidelines are meant to be a truly...Continue Reading

One of newest and most exciting approved treatments for cancer is the use of CAR-T therapy. CAR stands for chimeric antigen receptor and T stands for T-cell. Currently both Novartis (NVS) and Gilead (NASDAQ:GILD) have CAR-T therapies approved by the FDA. Axicabtagene (Yescarta) is sold by Gilead and is approved for refractory diffuse large b...Continue Reading

The human immune system is truly a wonder. It plays a critical role in our body’s defense to invading disease. Like a home security system, it is on alert 24/7/365. Through multiple mechanisms, it guards all our tissues, protects us from microbial foreign invaders, and removes cancer cells to keep us disease-free. For example, B...Continue Reading

A multidisciplinary team of researchers has developed an artificial intelligence platform that could enable doctors to prescribe personalized treatments for myeloma patients. A research group in Singapore has used artificial intelligence (AI) to identify optimized combinatorial drug treatments for myeloma, a type of blood cancer. Their methods and findings are published in Science Translational Medicine....Continue Reading